With their special structure and large surface area, MOFs open up new opportunities in drug delivery. The ability to exchange the metal centers and organic linkers even provide an extensive library of MOF materials. As a result, the integration of small guest molecules within the MOF pores, such as small molecule drugs and biomolecules, have shown promise for delivery applications to treat diseases. A recent review article discusses current proceedings on integrating diverse biomolecules within MOFs.
Integrating biomolecules with metal-organic frameworks