Nano-sized carrier systems have medical application in improving pharmacologic properties of bioactive agents. For many therapeutic approaches, it is important that the carrier system can stably incorporate the cargo during circulation without inducing aggregation, while cargo should ideally only be released after successful cellular uptake. These requirements have thus far only been met by chemistry approaches with nanoparticles that are difficult to characterize. Consequently, clinical translation of these systems has been very difficult to achieve.
Multifunctional nano-sized drug carriers based on reactive polypept(o)ides